Cefalexin (Cephalexin) Antimicrobial Susceptibility disks
Our Antibiotic disks contain, Cefalexin or cephalexin which is a first-generation cephalosporin antibiotic. Cefalexin is used to treat a number of infections including: otitis media, streptococcal pharyngitis, bone and joint infections, pneumonia, cellulitis, and urinary tract infections. It may be used to prevent bacterial endocarditis.It can also be used for the prevention of recurrent urinary-tract infections. It does not treat methicillin-resistant Staphylococcus aureus infections.
Cefalexin is a beta-lactam antibiotic of the cephalosporin family.It is bactericidal and acts by inhibiting synthesis of the peptidoglycan layer of the bacterial cell wall. As cefalexin closely resembles d-alanyl-d-alanine, an amino acid ending on the peptidoglycan layer of the cell wall, it is able to irreversibly bind to the active site of PBP, which is essential for the synthesis of the cell wall. It is most active against gram-positive cocci, and has moderate activity against some gram-negative bacilli. However, some bacterial cells have the enzyme β-lactamase, which hydrolyzes the beta-lactam ring, rendering the drug inactive. This contributes to antibacterial resistance towards cefalexin. The biological half-life of cefalexin is approximately 30 to 60 minutes
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Please note that these are not a universal fitting and only work in our convenient Disk Dispenser available from here