Bacitracin Antimicrobial Susceptibility disks
Our antibiotic disks contain Bacitracin which is a mixture of related cyclic polypeptides produced by organisms of the licheniformis group of Bacillus subtilis var Tracy. Bacitracin is a broad spectrum antibiotic. It targets both Gram-positive and Gram-negative bacteria, especially those that cause skin infections. Bacitracin is used in human medicine as a polypeptide antibiotic and is “approved by the U.S. Food and Drug Administration (FDA) for use in chickens and turkeys,”
Bacitracin interferes with the dephosphorylation of C55-isoprenyl pyrophosphate, and a related molecule known as bactoprenol pyrophosphate; both of these lipids function as membrane carrier molecules that transport the building-blocks of the peptidoglycan bacterial cell wall outside of the inner membrane.
Some have claimed that bacitracin is a protein disulfide isomerase inhibitor, but this is disputed by in vitro studies
Our 0.04µg Data sheet is available here.
Our 10U Data sheet is available here
Please note that these are not a universal fitting and only work in our convenient Disk Dispenser available from here